- 1907
Arrival of CICM Priest in the Philippines.
- 1928
Saint Mary’s School was established.
- 1967
The CICM Congregation took over the management and ownership of the school from the Parish.
- 1978
50th founding anniversary of Saint Mary’s College (elementary)
- 1984
Dr. Leopoldo Felix G. Saquing was appointed as Grade School Principal, the first lay person to occupy the position.
- 1994
SMU celebrated its 50th founding anniversary.
- 1995
Saint Mary’s College was elevated to University Status with Rev. Fr. John Van Bauwel, CICM, as the First University President.
- 1998
Rev. Jessie M. Hechanova, CICM, was installed as SMU’s Second University President.
- 1999
SMU Elementary Central and Training Department were merged.
- 2000
SMU Grade School opened Nursery with 67 pupil enrollees.
- 2003
SMU celebrated its Diamond Jubilee.
- 2005
Rev. Manuel D. Valencia, CICM, was installed as the Third University President on August 27, 2005.
- 2007
1st CICM School Friendship Meet was held in SMU in November 19-21, 2007. Grade School pupils competed in sports, cultural, and academic events.
- 2008
SMU Grade School completed the Preschool Department: Nursery, Kindergarten, and Preparatory.
- 2009
Dr. Samuel R. Soliven was appointed principal after Dr. Leopoldo Felix Saquing retired. Dr. Macrino A. Raymundo, was appointed Assistant Principal.
- 2010
Dr. Macrino A. Raymundo was appointed as Preschool & Grade School principal.
- 2013
Dr. Ma. Cristeta M. Aduca was appointed as Officer-in-charge, Preschool and Grade School.
- 2014
Dr. Ma. Cristeta M. Aduca was appointed Principal, Pre-school and Grade School. SMU Grade School renamed the levels in the Pre-school Department as: Nursery, Junior Kindergarten, and Kindergarten to align them to the K to 12 Basic Education Program.